Parathyroid Gland Removal Surgery in Melbourne
Parathyroidectomy is a surgical procedure to remove one or more overactive parathyroid glands that produce excess parathyroid hormone (PTH) and elevate blood calcium levels. The condition, called primary hyperparathyroidism, is most commonly caused by a single benign tumour of the parathyroid glands, known as a parathyroid adenoma.
At Specialist Surgical Group, our Melbourne-based endocrine surgeons perform parathyroidectomy using minimally invasive techniques, including a focused approach through a 2-3 cm incision when pre-operative imaging identifies a single abnormal gland. Intraoperative PTH monitoring is used to confirm successful removal before the wound is closed. Read more about our endocrine surgery services.
We consult from our Essendon and Bundoora clinics, with procedures performed at accredited hospitals in Melbourne. Most patients are discharged the same day or after one overnight stay.
Call us today at (03) 9466 7338 to book a consultation.
Book Consultation
Mon – Fri: 9 AM – 5 PM
We are located in the heart of Essendon and Bundoora.
Is parathyroidectomy for you?
Parathyroidectomy is considered when hyperparathyroidism is causing symptoms, complications, or biochemical changes significant enough to warrant surgical correction. It may be appropriate for you if:
- You have elevated blood calcium with elevated or inappropriately normal PTH levels, confirming primary hyperparathyroidism
- Your hyperparathyroidism is caused by a parathyroid adenoma or parathyroid hyperplasia, confirmed on imaging or biochemistry
- You have developed complications such as osteoporosis, kidney stones, or impaired kidney function
- You experience symptoms, including bone pain, muscle weakness, fatigue, or cognitive difficulties that affect your quality of life
- You have asymptomatic primary hyperparathyroidism meeting surgical criteria, such as a serum calcium level more than 0.25 mmol/L above the upper limit of normal, a T-score below -2.5 on bone density scan, or age under 50
- You are committed to post-operative follow-up, including calcium monitoring in the weeks after surgery
During your initial consultation, your surgeon will review your biochemistry, imaging studies, and symptoms to determine whether parathyroidectomy is the right treatment for you.
Potential benefits
- High cure rate. When performed by experienced endocrine surgeons at high-volume centres, parathyroidectomy achieves cure rates of 95-98%, with intraoperative PTH monitoring further improving surgical confidence and reducing the need for re-operation [1].
- Improved bone density. Parathyroidectomy produces significant, sustained gains in bone mineral density. A 2022 randomised controlled trial found significant increases in bone density at all measured sites in patients who underwent surgery, compared with those managed with observation alone [2].
- Reduction in kidney stone risk. Surgical treatment of hyperparathyroidism significantly reduces the risk of developing new kidney stones, with most studies demonstrating a clear reduction in stone events following parathyroidectomy [3].
- Symptom relief and quality of life improvements. Patients commonly report improvements in fatigue, muscle weakness, bone pain, and cognitive function following successful surgery. A 2022 systematic review confirmed meaningful quality of life gains in patients with both symptomatic and asymptomatic primary hyperparathyroidism who underwent parathyroidectomy [4].
- Biochemical normalisation. PTH levels typically fall within minutes of removing the abnormal gland, with blood calcium normalising over the following days to weeks [1].
- Minimally invasive procedure. The focused approach involves a small 2-3 cm incision, takes approximately 20-40 minutes for a single adenoma, and allows same-day discharge for most patients [5].
- Long-term resolution. For the majority of patients with a single parathyroid adenoma, parathyroidectomy provides a permanent cure, eliminating the need for lifelong medical management and monitoring of high calcium levels [1].
Potential risks
- Hypocalcaemia (low blood calcium). Temporary low calcium levels are common in the days following surgery, as the remaining parathyroid glands, which may have been suppressed by the overactive gland, resume normal function. Calcium and vitamin D supplementation are prescribed routinely after surgery.
- Hungry bone syndrome. In patients with significant pre-existing bone disease, rapid calcium uptake by bones after surgery can cause prolonged hypocalcaemia, requiring extended supplementation. This is more likely in patients with severely elevated pre-operative PTH levels or advanced osteoporosis [7].
- Recurrent laryngeal nerve injury. The nerve controlling the vocal cords runs close to the operative field. Temporary hoarseness occurs in a small proportion of patients; permanent voice change is uncommon when the procedure is performed carefully by an experienced surgeon [8].
- Persistent or recurrent hyperparathyroidism. In approximately 2-5% of cases, hyperparathyroidism persists after surgery, typically due to a missed adenoma, ectopic parathyroid tissue, or multigland disease not identified pre-operatively. Re-operation or further imaging may be required [1].
- General surgical risks. Bleeding requiring reoperation, wound infection, and anaesthetic reactions occur infrequently. The small incision and short operative time of focused parathyroidectomy reduce the overall burden of these risks compared to more extensive neck surgery [8].
Book a consultation today
(03) 9466 7338Meet our endocrine surgeon
Our endocrine surgeon is a Fellow of the Royal Australasian College of Surgeons with subspecialty training in endocrine, bariatric, and laparoscopic surgery, and has performed hundreds of thyroid, parathyroid, and adrenal procedures across Melbourne.
Your parathyroid gland removal journey
The following steps provide a brief overview of your journey for parathyroid gland removal surgery. Individual experiences will vary based on your specific health circumstances.
1. Initial consultation and health assessment
Your surgeon will review your biochemistry results, symptoms, and any prior imaging. The diagnosis of primary hyperparathyroidism will be confirmed, and the likely cause discussed.
If localisation imaging (such as a sestamibi scan or ultrasound) has not already been completed, this will be arranged to identify the abnormal gland and guide the surgical approach.
2. Pre-operative preparation
You will receive instructions covering fasting requirements, medication management, and what to expect on the day.
If imaging clearly identifies a single adenoma, a focused parathyroidectomy will be planned.
If results are discordant or multigland disease is suspected, a bilateral neck exploration may be required and will be discussed with you beforehand.
3. The parathyroidectomy procedure
Parathyroidectomy is performed under general anaesthesia at an accredited Melbourne hospital and takes approximately 20-40 minutes for a single adenoma, though bilateral exploration takes longer.
A 2-3 cm incision is made in a natural crease at the front of the neck. The abnormal gland is identified and removed. Intraoperative PTH monitoring is performed: a blood sample is taken 10-15 minutes after removal, and a drop in PTH of more than 50% confirms the overactive gland has been successfully excised. The wound is closed with dissolving sutures or surgical glue.
4. Recovery and discharge
Most patients wake comfortably and are able to eat and drink within a short time of surgery.
Calcium levels are checked by blood test before discharge, and calcium supplementation is prescribed as a precaution. Mild neck discomfort is common and managed with simple analgesia.
Most patients are discharged the same day or after one overnight stay, depending on their calcium levels and how far they live from the hospital.
5. Follow-up and monitoring
Your surgeon will see you 1-2 weeks after surgery to review your incision and confirm your biochemistry has normalised.
Calcium and PTH blood tests will be repeated at this appointment and again at 3-6 months to confirm a lasting cure.
Bone density may be reassessed over the following 1-3 years to monitor the recovery of bone health. Most patients require no further intervention once calcium and PTH levels are confirmed as normal.
Book a consultation today
(03) 9466 7338Parathyroidectomy surgery FAQ
For a focused parathyroidectomy targeting a single adenoma, the procedure typically takes 20-40 minutes. If a bilateral neck exploration is required to assess all four glands, the procedure takes longer, usually 60-90 minutes. Your surgeon will provide a more specific estimate based on your preoperative imaging and the planned surgical approach.
Most patients are discharged the same day. An overnight stay may be recommended if you live some distance from the hospital, have other medical conditions requiring monitoring, or if your post-operative calcium levels require observation. Your surgeon will confirm the likely length of stay at your pre-operative appointment.
Most patients can return to desk-based work within 2-3 days and resume all normal activities within 1-2 weeks. Heavy lifting and strenuous exercise should be avoided for 2 weeks to allow the neck incision to heal. We will provide specific guidance based on your occupation and recovery.
The cost of parathyroidectomy varies depending on the surgical approach, the hospital used, and your private health insurance policy. For medically indicated parathyroidectomy, Medicare provides a rebate on the surgeon’s fee under the relevant Medicare Benefits Schedule (MBS) item numbers.
Most patients with hospital-level private health insurance will have the main hospital costs covered, subject to any excess and applicable waiting periods. Out-of-pocket costs, which typically range from $1,500-$4,500 depending on your cover, will be itemised and quoted at your consultation. We encourage you to contact your insurer before booking.
Yes, most patients are prescribed calcium and vitamin D supplements for several weeks after surgery while the remaining parathyroid glands recover normal function. The duration varies depending on your pre-operative bone health and post-operative calcium levels. Most patients can stop supplements once their levels stabilise. Long-term supplementation is only required in the uncommon event of permanent hypoparathyroidism.
Biochemical cure, confirmed by normal PTH and calcium levels, is achieved in 95-98% of cases by experienced surgeons. However, some symptoms, particularly those related to bone health and fatigue, may take weeks to months to fully improve. If hyperparathyroidism persists after surgery, your surgeon will review the imaging and biochemistry and discuss whether further investigation or re-operation is indicated.
Many patients notice improvements in energy and general well-being within days to weeks of surgery. Cognitive symptoms such as brain fog and difficulty concentrating often improve over the first few months. Improvements in bone density take longer, typically becoming measurable on scan at 12 months and continuing over 2-3 years. Reduction in kidney stone risk is more immediate following normalisation of calcium levels.
Experienced endocrine surgeons achieve cure rates of 95-98% with parathyroidectomy, and intraoperative PTH monitoring has further improved these outcomes by providing real-time confirmation of successful gland removal. For patients with a single adenoma, the cure is generally permanent, with low rates of recurrence over long-term follow-up [1].
These are distinct endocrine surgery procedures targeting different glands. Thyroid gland surgery (thyroidectomy) treats thyroid cancer, large nodules, goitre, and hyperthyroidism. Adrenal gland surgery (adrenalectomy) addresses hormone-producing adrenal tumours.
Parathyroidectomy is generally a shorter and less complex procedure than either, and most patients are discharged the same day. All three procedures are performed by our endocrine surgery team and can be discussed at the same consultation if relevant.
Medical disclaimer
The information on this page is for general educational purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations, and does not create a doctor-patient relationship. Individual circumstances vary significantly, and nothing on this page should be used as a substitute for personalised advice from a qualified medical professional.
If you have concerns about your health, please seek medical attention promptly. To discuss your specific condition and treatment options with our team, please book a consultation by calling us at (03) 9466 7338.
References
[1] Wilhelm SM, Wang TS, Ruan DT, et al. The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism. JAMA Surg. 2016;151(10):959-968. https://doi.org/10.1001/jamasurg.2016.2310
[2] Lundstam K, Pretorius M, Bollerslev J, et al. Positive effect of parathyroidectomy compared to observation on BMD in a randomised controlled trial of mild primary hyperparathyroidism. J Bone Miner Res. 2022;37(11):2293-2307. https://doi.org/10.1002/jbmr.4685
[3] Mollerup CL, Vestergaard P, Frokjaer VG, et al. Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ. 2002;325(7368):807. https://doi.org/10.1136/bmj.325.7368.807
[4] Ejlsmark-Svensson H, Rolighed L, Harsløf T, et al. Health-related quality of life in primary hyperparathyroidism: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2022;107(11):3044-3052. https://doi.org/10.1210/clinem/dgac423
[5] Udelsman R, Lin Z, Donovan P. The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism. Ann Surg. 2011;253(3):585-591. https://doi.org/10.1097/SLA.0b013e318208fed9
[6] Bilezikian JP, Khan AA, Silverberg SJ, et al. Evaluation and management of primary hyperparathyroidism: summary statement and guidelines from the Fifth International Workshop. J Bone Miner Res. 2022;37(11):2293-2307. https://doi.org/10.1002/jbmr.4677
[7] Witteveen JE, van Thiel S, Romijn JA, Hamdy NA. Hungry bone syndrome: still a challenge in the post-operative management of primary hyperparathyroidism: a systematic review of the literature. Eur J Endocrinol. 2013;168(3):R45-53. https://doi.org/10.1530/EJE-12-0528
[8] Bergenfelz A, Jansson S, Kristoffersson A, et al. Complications to thyroid and parathyroid surgery: results as reported in a database from a multicentre audit comprising 3,660 patients. Langenbecks Arch Surg. 2008;393(5):667-673. https://doi.org/10.1007/s00423-008-0366-7
